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APY29 occupies IRE1α's kinase ATP-binding site to activate RNase-mediated XBP1 mRNA splicing even without upstream endoplasmic reticulum stress
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo
24) with pure antagonism
2013 Sep 24
TAS-301 - CAS# 193620-69-8 002euronal-LSB3i APY29 occupies IRE1α's kinase ATP-bindingTAS 301, CAS No. 193620 69 8, is a potent and selective constrictive remodeling regulator on renarrowing after balloon overstretch injury of porcine coronary artery. TAS 103 inhibits smooth muscle cell migration and proliferation. TAS 103 inhibits intimal thickening after balloon injury to rat carotid arteries. TAS 301 blocks receptor operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth
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