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KN-93 Phosphate - CAS# 1188890-41-6 Catalog No.:M6714-2 PubMed Central PMCID: PMC4682489

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Description

PubMed Central PMCID: PMC4682489

highly selective mitogen-activated protein kinase kinase 1/2 inhibitor

Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway

Formula: C22H23ClFN5O3

KN-93 Phosphate - CAS# 1188890-41-6 Catalog No.:M6714-2 PubMed Central PMCID: PMC4682489KN 93 Phosphate, CAS No. 1188890 41 6, is a CaMKII inhibitor. KN 93 suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR. KN 93 inhibits androgen receptor activity and induces cell death irrespective of p53 and Akt status in prostate cancer. KN 93 ameliorates levodopa induced dyskinesia in a rat model of Parkinson's disease. KN 93 protects rat cerebral cortical neurons from N methyl D aspartic acid induced injury. Product

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