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APJ receptor agonist 1 Size:Contact [email protected] for quotation Salicylic acid inhibits cyclo-oxygenase-2 (COX-2)

SKU: 13134358570

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Description

Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation

DMU2139 shows 88 and 133-fold selectivity for CYP1B1 over CYP1A1 and CYP1A2

InChiKey: ADSYMQORONDIDD-ZJHVPRRPSA-N

InChi: InChI=1S/C67H118N26O17/c1-35(2)30-45(61(106)88-43(22-15-29-81-67(77)78)57(102)89-44(23-24-49(71)95)59(104)87-41(20-10-12-26-69)58(103)92-47(32-50(72)96)62(107)93-52(36(3)4)64(109)110)91-63(108)48(34-94)84-51(97)33-82-55(100)40(19-9-11-25-68)86-56(101)42(21-14-28-80-66(75)76)85-53(98)37(5)83-60(105)46(31-38-16-7-6-8-17-38)90-54(99)39(70)18-13-27-79-65(73)74/h6-8

APJ receptor agonist 1 Size:Contact [email protected] for quotation Salicylic acid inhibits cyclo-oxygenase-2 (COX-2)APJ receptor agonist 1, a biphenyl acid derivative, is a potent APJ receptor (APJ R) agonist (EC50s 0. 093 and 0. 12 nM for human and rat APJ R, respectively). APJ receptor agonist 1 displays in vitro potency to apelin 13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 has the potential for the research of heart failure. Product information CAS Number: 2287153 38 0 Molecular Weight: 524. 01 Formula: C31H26ClN3O3 Chemical

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