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Formula: C39H65N5O8
Effect of chronic antipsychotic treatment on striatal phosphodiesterase 10A levels: a [¹¹C]MP-10 PET rodent imaging study with ex vivo confirmation
Molecular Weight: 437
SR18662 shows improved efficacy in reducing viability of multiple CRC cell lines
PHA-793887 )hydrazono)butane-1 3-dione Formula: C39H65N5O8PHA 793887 is an inhibitor of multiple cyclin dependent kinases (CDK) with activity against CDK2, CDK1 and CDK4. PHA 793887 was cytotoxic for leukemic cell lines in vitro, with IC(50) ranging from 0. 3 to 7 microM. In colony assays PHA 793887 showed very high activity against leukemia cell lines, with an IC(50) <0. 1 microM indicating that it has efficient and prolonged antiproliferative activity. PHA 793887 induced cell cycle arrest, inhibited Rb and
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