Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 3 - Aug 8
40-octakis(hydroxymethyl)-2
Chemical Name: (4S)-5-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[2-[[(2R)-1-[[(2R)-4-amino-1-[[(2R)-6-amino-1-[[2-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[2-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[2-[[2-[[(2R)-1-[[(2R)-1-[[(2R)-1-[[(1R)-1-carboxyethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-1
6-trichloro-3-methoxy-5-methylphenoxy)-6-({[(2R
Formula: C27H35F3N4O11
SR 1824 Catalog No.:M22508-C 40-octakis(hydroxymethyl)-2Ki = 10 nM SR 1824 is a non agonist PPAR ligand. Peroxisome proliferator activated receptor (PPAR) can be activated by the anti diabetes drugs known as thiazolidinediones, including rosiglitazone and pioglitazone. Phosphorylation of PPAR by cyclin dependent kinase 5 (Cdk5) leads to dysregulation of genes whose expression is altered in obesity, such as adiponectin. In vitro: In a previous study, SR1824 was characterized for its ability to block Cdk5
US$ 29.99
US$ 24.99
US$ 65.99
US$ 22.99
US$ 108.00
US$ 136.00
US$ 123.50
US$ 82.00
US$ 112.00
US$ 112.00
US$ 112.00