TAE-1 ethylbenzenesulfonate Smiles: CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1

Smiles: CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1

Nur77 modulator 1 is a good Nur77 binder (KD = 3

3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide

InChi: InChI=1S/C22H25N7O2/c1-29-11-13(9-25-29)20-16-10-24-28-21(30)15-7-14(8-17(27-20)18(15)16)26-22(31)19(23)12-5-3-2-4-6-12/h7-12

TAE-1 ethylbenzenesulfonate Smiles: CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1IC50: 0. 3 0. 02 M for AChE; 3. 9 0. 2 M for BuChE TAE 1 is an inhibitor of amyloid fibril formation and aggregation. Alzheimers disease (AD), a progressive neurodegenerative disorder, is characterized by the cerebral accumulation of insoluble aggregates of amyloid peptides (A). Although the precise mechanisms governing neuronal loss remains ambiguous, toxicity resulting from A activated pathways is evident. In vitro: In a previous study, the authors