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Molecular Weight: 386
Raloxifene binds to estrogen receptors (ER) as a mixed estrogen agonist/antagonist
PubMed PMID: 27306340
Smiles: CC1C=CSC=1C(=CCCN1C[C@@H](CCC1)C(O)=O)C1SC=CC=1C
(R)-CR8 trihydrochloride Size:10mg solid Molecular Weight: 386(R) CR8 (CR8) trihydrochloride, a second generation analog of Roscovitine, is a potent CDK1 2 5 7 9 inhibitor. (R) CR8 trihydrochloride inhibits CDK1 cyclin B (IC50=0. 09 M), CDK2 cyclin A (0. 072 M), CDK2 cyclin E (0. 041 M), CDK5 p25 (0. 11 M), CDK7 cyclin H (1. 1 M), CDK9 cyclin T (0. 18 M) and CK1 (0. 4 M). (R) CR8 trihydrochloride induces apoptosis and has neuroprotective effect. (R) CR8 trihydrochloride acts as a molecular glue degrader that