Cilofexor mol hemisulfate is a potent monoamine transporter

is a potent monoamine transporter inhibitor

7 cells with an IC50 of 10

SB-267268 (60 mg/kg

Epub 2018 Nov 13

Cilofexor mol hemisulfate is a potent monoamine transporterCilofexor (GS 9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC50 of 43 nM. Cilofexor has anti inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research. Product information CAS Number: 1418274 28 8 Molecular Weight: 586. 85 Formula: C28H22Cl3N3O5 Chemical Name: 2 [3 (2 chloro 4 {[5 cyclopropyl 3 (2,6 dichlorophenyl) 1,2