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Lometrexol hydrate - CAS# 1435784-14-7 Size:2mg solid Topiramate is used to treat

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Description

Topiramate is used to treat epilepsy in children and adults

PubMed PMID: 25515519

33(11):12760-12767

An introductory study

Lometrexol hydrate - CAS# 1435784-14-7 Size:2mg solid Topiramate is used to treatLometrexol hydrate (DDATHF hydrate), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity. Lometrexol hydrate also is a potent human Serine

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