Bis-sulfone-PEG3-Azide - CAS# 1802908-01-5 rteolol Hydrochloride M23 formation with IC50s of

M23 formation with IC50s of 5

109(41):9206-12

[Epub ahead of print] PubMed PMID: 26555927

This is in the same potency range as the value for axin2 increase (EC50=319 nM)

Bis-sulfone-PEG3-Azide - CAS# 1802908-01-5 rteolol Hydrochloride M23 formation with IC50s ofBis sulfone PEG3 Azide is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 1802908 01 5 Molecular Weight: 700. 82 Formula: C33H40N4O9S2 Chemical Name: N (2 {2 [2 (2 azidoethoxy)ethoxy]ethoxy}ethyl) 4 [3 (4 methylbenzenesulfonyl) 2 [(4 methylbenzenesulfonyl)methyl]propanoyl]benzamide Smiles: CC1C=CC(=CC=1)S(=O)(=O)CC(CS(=O)(=O)C1C=CC(C)=CC=1)C(=O)C1C=CC(=CC=1)C(=O)NCCOCCOCCOCCN=[N+]=[N ]