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1415560-64-3 (TFA)
Targeting the YAP/TAZ transcriptional target cyclooxygenase 2 (COX-2) using celecoxib inhibits cell proliferation and tumorigenesis in NF2 mutant cells
Roberts BJ
EOL-1 xenograft growth delay
BI-3663, PTK2/FAK PROTAC 632 1415560-64-3 (TFA)BI 3663 is a highly selective PTK2 FAK PROTAC (DC50=30 nM), with cereblon ligands to hijack E3 ligases for PTK2 degradation. BI 3663 inhibits PTK2 with an IC50 of 18 nM. BI 3663 is a PROTAC that composes of BI 4464 (HY 124625) linked to Pomalidomide (HY 10984) with a linker. Anti cancer activity. Product information CAS Number: 2341740 84 7 Molecular Weight: 917. 84 Formula: C44H42F3N7O12 Chemical Name: N [2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3
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