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also known as Apabetalone
OTS514 --- TOPK inhibitor
Guichard SS
Simpson PB
ESI-09 - CAS# 263707-16-0 size:2mg solid also known as ApabetaloneESI 09, CAS No. 263707 16 0, is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC mediated Rap1 activation and Akt phosphorylation, as well as EPAC mediated insulin secretion in pancreatic cells. EPAC1 plays an important role in pancreatic cancer cell migration and invasion, and thus represents a potential target for developing novel therapeutic strategies for pancreatic cancer. Product
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