PROTAC SGK3 degrader-1 Size:2mg solid Smiles: CC1=CC(=C(C=C1C)C1=CC=C(/C=C2\C(=O)N(N=C\2C)C2C=CC(=CC=2)C(O)=O)O1)[N+]([O-])=O

Smiles: CC1=CC(=C(C=C1C)C1=CC=C(/C=C2\C(=O)N(N=C\2C)C2C=CC(=CC=2)C(O)=O)O1)[N+]([O-])=O

Solubility: DMSO up to 10 mM

3Na/c11-8-3-6(21(12

Formula: C26H30FN7O

PROTAC SGK3 degrader-1 Size:2mg solid Smiles: CC1=CC(=C(C=C1C)C1=CC=C(/C=C2\C(=O)N(N=C\2C)C2C=CC(=CC=2)C(O)=O)O1)[N+]([O-])=OPROTAC SGK3 degrader 1 (SGK3 PROTAC1), is a potent SKG3 degrader based on PROTAC. PROTAC SGK3 degrader 1 (0. 3 M) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate). Product information CAS Number: 2381320 35 8 Molecular Weight: 1157. 38 Formula: C57H73FN10O11S2 Chemical Name: (2S, 4R) 1 [(2S) 2 (2 {2 [2 ({6 [(2R) 2 [({6