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Three-way analysis of the UPLC-PDA dataset for themulticomponent quantitation of hydrochlorothiazide and olmesartan medoxomil intablets by parallel factor analysis and three-way partial least squares
is a potent and irreversible small-molecule inhibitor of FGFR4
4 nM) and members of the VEGFR
2016 May 6
Delamanid (OPC-67683) - CAS# 681492-22-8 60233 Three-way analysis of the UPLC-PDADelamanid (OPC 67683), CAS No. 681492 22 8, also known as OPC 67683, is a drug for the treatment of multi drug resistant tuberculosis. It works by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall. The drug is approved in the EU. Delamanid inhibits the synthesis of mycolic acids, crucial component of the cell wall of the Mycobacterium tuberculosis complex.