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Lifitegrast 19114 ZM39923 potently inhibits tissue transglutaminase

SKU: 24829157700

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Description

ZM39923 potently inhibits tissue transglutaminase (TGM2) with an IC50 of 10 nM

2014 Apr 6

24 hours) inhibits 25% cell number in comparation with those grown in the presence of vehicle[2]

Smiles: C[C@H]1CC[C@@H]2N(C1)C[C@@H]1[C@@H](CC[C@@H]3[C@H]1C[C@H]1[C@H]3CC(=O)[C@H]3C[C@H](CC[C@@]31C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@]2(C)O

Lifitegrast 19114 ZM39923 potently inhibits tissue transglutaminaseLifitegrast (SAR 1118) is an integrin lymphocyte function associated antigen 1 (LFA 1; L2) antagonist; inhibits Jurkat T cell attachment to ICAM 1 with an IC50 of 2. 98 nM. Product information CAS Number: 1025967 78 5 Molecular Weight: 615. 48 Formula: C29H24Cl2N2O7S Chemical Name: (2S) 2 {[2 (1 benzofuran 6 carbonyl) 5,7 dichloro 1,2,3,4 tetrahydroisoquinolin 6 yl]formamido} 3 (3 methanesulfonylphenyl)propanoic acid Smiles:

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