CC-90001 - a JNK inhibitor. CAS# 1403859-14-2 0225 and CDK1 with IC50 of

and CDK1 with IC50 of 35 nM

Smiles: O=C(NC1=CC(=CC=C1)NC1=NC(NCCCNC(=O)C2=CC=CS2)=C(I)C=N1)N1CCCC1

Deschloroclozapine is a potent agonist for hM3Dq with an EC50=0

1186/1756-8722-6-79

CC-90001 - a JNK inhibitor. CAS# 1403859-14-2 0225 and CDK1 with IC50 ofCC 90001 is a potent and selective JNK inhibitor. CC 90001 is 12. 9 fold more potent for JNK1 inhibition than JNK2 in a cell based model. CC90001 currently under clinical trials for the Treatment of Idiopathic Pulmonary Fibrosis. Product information CAS Number: 1403859 14 2 Molecular Weight: 321. 42 Formula: C16H27N5O2 Synonym: CC 90001 CC90001 Related CAS Number: 1946833 77 7 (HCl) 1946833 89 1 (tosylate) 1946833 91 5 (mesylate) 1946833 97 1