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Additional results suggest that BTZ043 efficacy is time-rather than dose-dependent
also known as ARN-509 and JNJ-56021927
128(2):357-64
123(33):7149-7156
Epirubicin Hydrochloride Size:Solid 2 mg Additional results suggest that BTZ043Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.