CAL-101 - CAS# 870281-82-6 richlormethiazide Chemical Name: (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone

Chemical Name: (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone

Solubility: DMSO: 9 mg/mL(34

also known as BMS-512148

2-d]pyrimidin-2-yl)thio]-acetamide

CAL-101 - CAS# 870281-82-6 richlormethiazide Chemical Name: (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanoneIdelalisib, also known as CAL 101, is a PI3K delta inhibitor with potential immunomodulating and antineoplastic activities. CAL 101 inhibits the production of the second messenger phosphatidylinositol 3,4,5 trisphosphate (PIP3), preventing the activation of the PI3K signaling pathway and thus inhibiting tumor cell proliferation, motility, and survival. Unlike other isoforms of PI3K, PI3K delta is expressed primarily in hematopoietic lineages. The