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NDT 9513727 can be used for the research of human inflammatory diseases
10(11): 2043-51
DuP-697 has no effect on phenylquinone writhing in rats (ED50 greater than 100 mg/kg)
6-difluorophenyl)methyl]-2-[4-(2-methylpropanamido)phenyl]-4-oxo-4H
PF-04856264 892al-Glu(OSu)-OH NDT 9513727 can be usedPF 04856264 is a potent and selective Nav1. 7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1. 7, respectively. PF 04856264 has low potency against the rat Nav1. 7 channel. PF 04856264 shows analgesic effect. Product information CAS Number: 1235397 05 3 Molecular Weight: 437. 49 Formula: C20H15N5O3S2 Chemical Name: 3 cyano 4 [2 (1 methyl 1H pyrazol 5 yl)phenoxy] N (1,3 thiazol 2 yl)benzene 1 sulfonamide