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mTOR-IN-1 inhibits NCI-PC3 and MCF7neo/Her2 cells proliferation with IC50s of 150 nM and 57 nM
daily for 15 weeks) activates AMPK and SIRT1 in vivo
Butyrolactone 3 shows weak inhibitory on CBP (IC50=0
Smiles: COC1=CC2=C(SCCCN)C3=CC(=CC=C3N=C2C=C1)OC
Alkyne-probe 1 or® 526 mTOR-IN-1 inhibits NCI-PC3 and MCF7neo/Her2Alkyne probe 1 is usually used as a Alkyne labeled chemical or fluorescent probe. Product information Molecular Weight: 293. 36 Formula: C14H23N5O2 Chemical Name: (2S) 6 amino 2 (but 3 ynoylamino) N [2 (3 methyldiazirin 3 yl)ethyl]hexanamide Smiles: CC1(CCNC(=O)[C@H](CCCCN)NC(=O)CC#C)N=N1 InChiKey: YXTWKPBYQQOHHD NSHDSACASA N InChi: InChI=1S C14H23N5O2 c1 3 6 12(20)17 11(7 4 5 9 15)13(21)16 10 8 14(2)18 19 14 h1,11H,4 10,15H2,2H3,(H,16,21)(H,17,20)
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