PROTAC BRD4 Degrader-12 - CAS# 2417370-90-0 Catalog No.:M35003-C Spectroscopic evaluation of synthesized 5β-dihydrocortisol

Spectroscopic evaluation of synthesized 5β-dihydrocortisol and 5β-dihydrocortisol acetate binding mechanism with human serum albumin and their role in anticancer activity

In vivo: The lowest ratio (CE/IC50 = 221) of 3F8 implied that 3F8 was more efficient in vivo

InChi: InChI=1S/C21H24N2O4/c1-3-12-10-23-17-8-14-13-6-4-5-7-16(13)22-18(14)21(23

D-I03 (0-10 μM

PROTAC BRD4 Degrader-12 - CAS# 2417370-90-0 Catalog No.:M35003-C Spectroscopic evaluation of synthesized 5β-dihydrocortisolPROTAC BRD4 Degrader 12 (compound 9c) is a PROTAC connected by ligands for von Hippel Lindau and BRD4. PROTAC BRD4 Degrader 12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0. 39 nM and 0. 24 nM, respectively. Product information CAS Number: 2417370 90 0 Molecular Weight: 1306. 58 Formula: C62H77F2N9O12S4 Chemical Name: (2S,4R) 1 [(2S) 2 (11 {[8 (3,5 difluoropyridin 2 yl) 4