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The disulfide bond of IPA-3 is critical for inhibition of Pak1 and in vitro reduction by the reducing agent dithiothreitol (DTT) abolishes Pak1 inhibition by IPA-3
InChiKey: RYHCACJBKCOBTJ-UHFFFAOYSA-N
treatment with Casein Kinase II Inhibitor IV leads to the upregulation of keratinocyte early differentiation marker genes
which may result in epigenetic changes in tumor cells and so tumor cell death
Br-PEG4-methyl acetate erazine The disulfide bond of IPA-3Br PEG4 methyl acetate is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information Molecular Weight: 329. 18 Formula: C11H21BrO6 Chemical Name: methyl 14 bromo 3,6,9,12 tetraoxatetradecanoate Smiles: COC(=O)COCCOCCOCCOCCBr InChiKey: HWNBXYOTWICDGW UHFFFAOYSA N InChi: InChI=1S C11H21BrO6 c1 14 11(13)10 18 9 8 17 7 6 16 5 4 15 3 2 12 h2 10H2,1H3 Technical Data Appearance: Solid Power Purity: 98% (or refer to the
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