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39(1):267-76
1-alpha]isoquinolin-4-one
InChiKey: SGZRQMALQBXAIQ-UHFFFAOYSA-N
Acute (5 g/kg) and chronic (25 and 250 mg/kg) toxicology studies in uninfected mice show that
Zoliflodacin 8317 39(1):267-76Zoliflodacin (ETX0914; AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram positive and Gram negative organisms, including S. aureus with the MIC90 of 0. 25 g mL. Product information CAS Number: 1620458 09 4 Molecular Weight: 487. 44 Formula: C22H22FN5O7 Chemical Name: (4'R,6'S,7'S) 17' fluoro 4',6' dimethyl 13' [(4S) 4 methyl 2 oxo 1,3 oxazolidin