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promoted cytokine independence and blocks differentiation in hematopoietic cells
CAS Number: 959860-85-6
InChi: InChI=1S/C68H84N12O9/c1-47-23-28-55(43-57(47)75-68-72-31-29-56(74-68)54-21-13-30-70-44-54)73-64(83)53-26-24-49(25-27-53)45-78-34-36-79(37-35-78)59(81)46-89-42-41-88-40-39-87-38-32-71-66(85)62(60(50-15-7-4-8-16-50)51-17-9-5-10-18-51)77-65(84)58-22-14-33-80(58)67(86)61(52-19-11-6-12-20-52)76-63(82)48(2)69-3/h4-5
a selective cathepsin K inhibitor
Thalidomide-4-OH rgenin promoted cytokine independence and blocksThalidomide 4 OH (Cereblon ligand 2) is the Thalidomide based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4 OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs. Product information CAS Number: 5054 59 1 Molecular Weight: 274. 23 Formula: C13H10N2O5 Synonym: Cereblon ligand 2 E3 ligase Ligand 2 Chemical Name: 2 (2, 6 dioxopiperidin 3 yl) 4 hydroxy 2, 3 dihydro 1H isoindole 1, 3 dione
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