IMR-1A hoquine phosphate CC1C=C(C=C(C)C=1N)C1=CC(C)=C(N)C(C)=C1

CC1C=C(C=C(C)C=1N)C1=CC(C)=C(N)C(C)=C1

also known as MLN-4924 and TAK-924

selective and ATP-competitive mTOR inhibitor (IC50 = 0

and colon cancer

IMR-1A hoquine phosphate CC1C=C(C=C(C)C=1N)C1=CC(C)=C(N)C(C)=C1IMR 1A, a acid metabolite of IMR 1, is a Notch inhibitor with an IC50 of 0. 5 M. IMR 1A has a 50 fold increase in potency with respect to IMR 1. IMR 1 can metabolize in vivo to IMR 1A. Product information CAS Number: 331862 41 0 Molecular Weight: 325. 36 Formula: C13H11NO5S2 Chemical Name: 2 (2 methoxy 4 {[(5E) 4 oxo 2 sulfanylidene 1, 3 thiazolidin 5 ylidene]methyl}phenoxy)acetic acid Smiles: COC1=CC(=CC=C1OCC(O)=O) C=C1 SC(=S)NC 1=O InChiKey: