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10-dihydroxy-5-methoxy-9
InChi: InChI=1S/C19H20O10/c20-6-11-15(25)17(27)18(28)19(29-11)13-10(23)5-9(22)12(16(13)26)14(24)7-1-3-8(21)4-2-7/h1-5
InChi: InChI=1S/C53H84NO14P/c1-32-18-14-13-15-19-33(2)44(63-8)30-40-23-21-38(7)53(61
InChiKey: OXSCPDKUZWPWFR-UHFFFAOYSA-N
NGB 2904 hydrochloride nedioic Acid 10-dihydroxy-5-methoxy-9NGB 2904 hydrochloride is a potent, selective, orally active and brain penetrated antagonist of dopamine D3 receptor, with a Ki of 1. 4 nM. NGB 2904 hydrochloride shows selectivity for D3 over D2, 5 HT2, 1, D4, D1 and D5 receptors (Kis=217, 223, 642, >5000, >10000 and >10000 nM, respectively). NGB 2904 hydrochloride antagonizes Quinpirole stimulated mitogenesis. NGB 2904 hydrochloride can inhibit Cocaine's rewarding effects and Cocaine induced
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