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CAS Number: 1069-66-5
Smiles: CC1C=C(C=C(C)C=1O)/C=C1\CC/C(=C\C2=CC(C)=C(O)C(C)=C2)/C\1=O
cebranopadol does not induce motor coordination deficits or respiratory depression in rats
orally active and dual TLR7/8 inhibitor with IC50s of 11
(Z)-Mirin Size:Contact [email protected] for quotation CAS Number: 1069-66-5Mirin is a small molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Target: in vitro: Mirin was shown to block Mre11 exonuclease activity and MRN dependent ATM activation, and to inhibit the ionizing radiation induced G2 M checkpoint and homologous recombination in mammalian cells. Mirin inhibition of ATM activation is independent of Mre11 nuclease inhibition since the M(HN)RN and M(HL DV)RN mutant complexes are inhibited equivalently to the
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