B-Raf inhibitor 1 dihydrochloride Catalog No.:M9061-10 74)66-42-17-15-41(16-18-42)52-63-53-45(31-61-65-53)55(64-52)79-34-44-33-67(21-23-78-44)20-8-6-7-9-22-75-24-25-76-26-27-77-35-49(70)62-51(57(3

74)66-42-17-15-41(16-18-42)52-63-53-45(31-61-65-53)55(64-52)79-34-44-33-67(21-23-78-44)20-8-6-7-9-22-75-24-25-76-26-27-77-35-49(70)62-51(57(3

It is a weak inhibitor of PKA with an IC50 of 30 μM

(2010) Cell

24 hours) is able to reduce cell viability in a dose-dependent manner in Neuro-2A

B-Raf inhibitor 1 dihydrochloride Catalog No.:M9061-10 74)66-42-17-15-41(16-18-42)52-63-53-45(31-61-65-53)55(64-52)79-34-44-33-67(21-23-78-44)20-8-6-7-9-22-75-24-25-76-26-27-77-35-49(70)62-51(57(3HUN85199, also known as B Raf inhibitor 1 dihydrochloride, is a novel potent and selective B Raf inhibitor. HUN85199 has CAS#1191385 19 9, was first reported in Journal of Medicinal Chemistry (2009), 52(20), 6189 6192. Product information CAS Number: 1191385 19 9 Molecular Weight: 551. 86 Formula: C26H21Cl3N8 Synonym: 1,5 Isoquinolinediamine, N1 (4 chlorophenyl) 6 methyl N5 [3 (9H purin 6 yl) 2 pyridinyl] , hydrochloride (1: 2) Chemical Name: N1 (4