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KM11060 partially corrects F508del-CFTR processing and increases surface expression to 75% of that observed in cells incubated at low temperature
Azelastine is shown to block secretion of IL-6
5 μM) suppresses the expression of TNF induced the expression of gene products involved in antiapoptosis (IAP1
Smiles: CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSCCCC(=O)N[C@@H](CC2=CC=C(C=C2)OC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
WH-4-025 - CAS# 1876463-35-2 EG10-azide KM11060 partially corrects F508del-CFTR processingWH 4 025 is a Salt inducible kinase (SIK) inhibitor (WO2016023014 A2). Product information CAS Number: 1876463 35 2 Molecular Weight: 741. 76 Formula: C39H38F3N7O5 Chemical Name: 2 methyl 5 ((3 (trifluoromethyl)phenyl)carbamoyl)phenyl (2, 4 dimethoxyphenyl)(2 ((4 (4 methylpiperazin 1 yl)phenyl)amino)pyrimidin 4 yl)carbamate Smiles: CN1CCN(CC1)C1C=CC(=CC=1)NC1=NC(=CC=N1)N(C1=CC=C(C=C1OC)OC)C(=O)OC1=CC(=CC=C1C)C(=O)NC1=CC(=CC=C1)C(F)(F)F InChiKey:
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