1, 1, 1-Trifluoroethyl-PEG2-propargyl Catalog No.:M26900-C JBJ-02-112-05 demonstrates mutant selectivity by

JBJ-02-112-05 demonstrates mutant selectivity by inhibiting mutant EGFR and downstream AKT and ERK1/2 phosphorylation in Ba/F3 cells stably transfected with EGFRL858R

The high levels of PARP expression confirmed the DNA breaks upon conjugate treatment

Chemical Name: 1-({4-ethyl-5-[5-(4-phenoxyphenyl)-1

AZD-3161 (10 μmol/kg

1, 1, 1-Trifluoroethyl-PEG2-propargyl Catalog No.:M26900-C JBJ-02-112-05 demonstrates mutant selectivity by1,1,1 Trifluoroethyl PEG2 propargyl is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1835759 73 3 Molecular Weight: 226. 19 Formula: C9H13F3O3 Chemical Name: 1,1,1 trifluoro 2 {2 [2 (prop 2 yn 1 yloxy)ethoxy]ethoxy}ethane Smiles: C#CCOCCOCCOCC(F)(F)F InChiKey: HILROVSZUWJRKP UHFFFAOYSA N InChi: InChI=1S C9H13F3O3 c1 2 3 13 4 5 14 6 7 15 8 9(10,11)12 h1H,3 8H2 Technical Data Appearance: Solid