Necrostatin-34 Catalog No.:M17258-C InChi: InChI=1S/C51H67N9O6/c1-31(2)25-41(46(54)61)56-48(63)42(26-32(3)4)58-51(66)45(29-36-30-55-40-23-11-10-21-38(36)40)60-49(64)43(27-33-15-6-5-7-16-33)59-50(65)44(57-47(62)39(53)22-12-13-24-52)28-35-19-14-18-34-17-8-9-20-37(34)35/h5-11

Name: Necrostatin-34 Catalog No.:M17258-C InChi: InChI=1S/C51H67N9O6/c1-31(2)25-41(46(54)61)56-48(63)42(26-32(3)4)58-51(66)45(29-36-30-55-40-23-11-10-21-38(36)40)60-49(64)43(27-33-15-6-5-7-16-33)59-50(65)44(57-47(62)39(53)22-12-13-24-52)28-35-19-14-18-34-17-8-9-20-37(34)35/h5-11
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Description

InChi: InChI=1S/C51H67N9O6/c1-31(2)25-41(46(54)61)56-48(63)42(26-32(3)4)58-51(66)45(29-36-30-55-40-23-11-10-21-38(36)40)60-49(64)43(27-33-15-6-5-7-16-33)59-50(65)44(57-47(62)39(53)22-12-13-24-52)28-35-19-14-18-34-17-8-9-20-37(34)35/h5-11

12 h) enhances invasion of glioma cells

Smiles: C[C@H](OC1=CC=C(C)C2=NC(=CC(C(=O)O[Na])=C12)C1OC2=CC=CC=C2C=1C)C1CCOCC1

LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms

Necrostatin-34 Catalog No.:M17258-C InChi: InChI=1S/C51H67N9O6/c1-31(2)25-41(46(54)61)56-48(63)42(26-32(3)4)58-51(66)45(29-36-30-55-40-23-11-10-21-38(36)40)60-49(64)43(27-33-15-6-5-7-16-33)59-50(65)44(57-47(62)39(53)22-12-13-24-52)28-35-19-14-18-34-17-8-9-20-37(34)35/h5-11Necrostatin 34 (Nec 34), a RIPK1 kinase inhibitor, stabilizes RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain. Product information CAS Number: 375835 43 1 Molecular Weight: 384. 48 Formula: C18H16N4O2S2 Chemical Name: 2 {[3 cyano 4 (4 methylphenyl) 6 oxo 1, 4, 5, 6 tetrahydropyridin 2 yl]sulfanyl} N (1, 3 thiazol 2 yl)acetamide Smiles: CC1C=CC(=CC=1)C1CC(=O)NC(SCC(=O)NC2=NC=CS2)=C1C#N InChiKey:

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