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18(13):3616-27
In an intracellular Ca2+ (iCa2+) mobilization assay using HT29 colon cancer cells
GSK2334470 also inhibited T-loop phosphorylation and activation of Akt
2018 Mar 10
Milademetan hioinosine 18(13):3616-27Milademetan (DS 3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS 3032) induces G1 cell cycle arrest, senescence and apoptosis. Product information CAS Number: 1398568 47 2 Molecular Weight: 618. 53 Formula: C30H34Cl2FN5O4 Chemical Name: (3'R,4'S,5'R) N [(3R,6S) 6 carbamoyloxan 3 yl] 6'' chloro 4' (2 chloro 3 fluoropyridin 4 yl) 4,4 dimethyl 2'' oxo 1'',2''
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