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selective for S1P1 (EC50 ~0
It can also cause a reduction in Aβ40 and Aβ42 levels in human primary neuronal cells (IC50 ~115 nM for total Aβ and ~200 nM for Aβ42) and in brain extracts
LY2157199 treatment stimulates hematopoiesis from primary MDS bone marrow specimens
SAR439859 is a potent estrogen receptor (ER) antagonist with EC50 of 0
Sarpogrelate Hydrochloride - CAS# 135159-51-2 penem pivoxil(L-084) selective for S1P1 (EC50 ~0Sarpogrelate is a drug which acts as an antagonist at the 5HT2A and 5 HT2B receptors. It blocks serotonin induced platelet aggregation, and has applications in the treatment of many diseases including diabetes mellitus, Buerger's disease, Raynaud's disease, coronary artery disease, angina pectoris, and atherosclerosis. Product information CAS Number: 135159 51 2 Molecular Weight: 465. 97 Formula: C24H32ClNO6 Synonym: Anplag MCI 9042 MCI9042 MCI 9042