pNSC-CSB size:1000X; 0.5 ml ZCL278 directly binds to the

ZCL278 directly binds to the binding site of the Cdc42 guanine nucleotide exchange factor intersectin (ITSN) and inhibits its functions (Kd ~6-11 µM)

Azacitidinum

PD158780 produces a significant therapeutic effect against the estrogendependent MCF-7 breast carcinoma at equitoxic dose levels

Incubation of pre-T-LBL cells with (Z)-SMI-4a induced G1 phase cell-cycle arrest secondary to a dose-dependent induction of p27(Kip1)

pNSC-CSB size:1000X; 0.5 ml ZCL278 directly binds to theProduct Information Purity: 98% for each compound Storage: 4oC for 1 month. 20oC for 3 month. Cocktail Formulation: 3 mM CHIR99021 and 2 mM SB431542 in DMSO solution Effective Concentration in Cell Culture: 3 M CHIR99021 and 2 M SB431542 in cell culture medium Biological Activity: A major challenge of the current hESC iPSC differentiation paradigm is the inability to effectively capture and long term, stably expand lineage specific stem cells that