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AQ-RA 741 togramin-1 Cinepazide Maleate is a maleate

SKU: 43936435117

4.8
USD100.00 USD127.00

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Description

Cinepazide Maleate is a maleate salt form of cinepazide which is a vasodilator

SAR-260301 is well tolerated at the active dose

Smiles: CN(C)CCNC(=O)COC1C2CC3C=CC=C(CC4C=CC=C(CC5=CC=CC(CC=1C=CC=2)=C5OCC(=O)NCCN(C)C)C=4OCC(=O)NCCN(C)C)C=3OCC(=O)NCCN(C)C

Mice receiving AX-024 rapidly recovers from neurological impairment and weight loss

AQ-RA 741 togramin-1 Cinepazide Maleate is a maleateAQ RA 741 is a potent and selective M2 antagonist, with high affinity for cardiac M2 sites (pKi = 8. 30) . The M2 muscarinic receptor subtype is involved in the regulation of heart rate, mediating muscarinic receptor dependent movement, antinociceptive responses and temperature control . In radioligand binding studies, the affinity of AQ RA 741 for cardiac M2 sites, cortical M1 sites and grandular M3 sites are of pKi values of 8. 30, 7. 70 and 6. 82,

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