PI3Kα/mTOR-IN-1 Catalog No.:M18955-C H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15

H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15

Intravenously infused Caldaret (3 or 30 microg/kg per hour) for 30 min at left circumflex (LCX)-reperfusion markedly reduces infarct size (by 51

as well as decreased expressions of collagen II and aggrecan

InChi: InChI=1S/C21H19Cl2N5O2/c1-13(21-17(22)10-24-11-18(21)23)30-15-3-5-20-16(8-15)19(26-27-20)4-2-14-9-25-28(12-14)6-7-29/h2-5

PI3Kα/mTOR-IN-1 Catalog No.:M18955-C H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15PI3K mTOR IN 1 is a potent PI3K mTOR dual inhibitor, with an IC50 of 7 nM for PI3K in a cell assay, and Kis of 10. 6 nM and 12. 5 nM for mTOR and PI3K in a cell free assay , respectively. Product information CAS Number: 1013098 90 2 Molecular Weight: 310. 35 Formula: C16H18N6O Chemical Name: 2 amino 8 cyclopentyl 4 methyl 6 (1H pyrazol 4 yl) 7H,8H pyrido[2,3 d]pyrimidin 7 one Smiles: CC1N=C(N)N=C2C=1C=C(C(=O)N2C1CCCC1)C1=CNN=C1 InChiKey: