GSK-3787 - CAS# 188591-46-0 60167 potent and selective inhibitor of

potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant (IC50 for LRRK2-wild-type ~20

The activity ofGNE-617 hydrochloride is evaluated on a panel 53 non-small cell lung cancer (NSCLC) cell lines in the presence or absence of 10 μM nicotinic acid

SBI-0206965 was usually used at 10 µM final concentration in vitro

PubMed PMID: 19808981

GSK-3787 - CAS# 188591-46-0 60167 potent and selective inhibitor ofGSK 3787, CAS No. 188591 46 0, is a selective and irreversible peroxisome proliferator activated receptor delta (PPARdelta) antagonist with good pharmacokinetic properties. GSK3787 can antagonize PPARbeta delta in vivo, thus providing a new strategy to delineate the functional role of a receptor with great potential as a therapeutic target for the treatment and prevention of disease. Product information CAS Number: 188591 46 0 Molecular Weight: 392.