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17-32)15-23(25)34/h7
Formula: C17H22BrNO4
Chemical Name: (2S)-3-methyl-2-(N-{[2'-(1H-1
OC1=NC=CC2C1=CC=CC=2S(=O)(=O)N1CCCNCC1
Rocaglamide D012612 17-32)15-23(25)34/h7Rocaglamide (Roc A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF B activation in T cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia. Product
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