G-744 Catalog No.:M30056-C Smiles: CCCCCC1C=CC(/C=C/C(=O)NC2C=C(Cl)C=CC=2C(O)=O)=CC=1

Smiles: CCCCCC1C=CC(/C=C/C(=O)NC2C=C(Cl)C=CC=2C(O)=O)=CC=1

reversible increase in serum creatinine

Barrett PH

every 3 rd day

G-744 Catalog No.:M30056-C Smiles: CCCCCC1C=CC(/C=C/C(=O)NC2C=C(Cl)C=CC=2C(O)=O)=CC=1G 744 is a highly potent, selective and orally active Btk inhibitor with an IC50 of 2 nM. G 744 is metabolically stable, well tolerated and efficacious to treat arthritis. Product information CAS Number: 1346669 54 2 Molecular Weight: 527. 64 Formula: C29H29N5O3S Chemical Name: 10 [2 (hydroxymethyl) 3 {1 methyl 6 oxo 5 [(pyrimidin 4 yl)amino] 1,6 dihydropyridin 3 yl}phenyl] 4,4 dimethyl 7 thia 10 azatricyclo[6. 4. 0. 0,]dodeca 1(8),2(6) dien 9 one