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3-benzodioxole-5-carboxylate
4-dichlorophenyl)ethyl}-1H-imidazole
6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2
01) and further lowered to 68% of control at 10 µM
Duocarmycin A F265 3-benzodioxole-5-carboxylateDuocarmycin A, which is one of well known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3 end of AT rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC 2 cells typically apoptotic changes, including chromatin condensation, sub G1 accumulation in DNA histogram pattern, and decrease in procaspase 3 and 9 levels. Product information CAS Number: 118292 34 5 Molecular Weight: 507. 49
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