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and an increased escape latency of rats in the Morris water maze test
Adv Exp Med Biol
the delta and gamma isoforms are overexpressed primarily in hematologic malignancies and inflammatory and autoimmune diseases
MPI-0479605 does not show inhibitory activity via daily dosing on the Colo-205 xenografts
Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 and an increased escape latencySu 11274, CAS No. 658084 23 2, is a selective Met tyrosine kinase inhibitor with IC50 of 10 nM. Su 11274 increases tumorigenicity and enriched for melanoma initiating cells by bioenergetic modulation. Su 11274 suppresses proliferation and motility of pancreatic cancer cells. Su 11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation. Su 11274 exhibits a selective inhibition pattern toward different receptor mutated
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