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ATX inhibitor 5 20529 Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(NC2=CC=C(C=C2)N2CCN(CCOCCOCCNC(=O)CNC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CC2)=NC=C1Cl

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Description

Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(NC2=CC=C(C=C2)N2CCN(CCOCCOCCNC(=O)CNC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CC2)=NC=C1Cl

Smiles: CCCCCCCCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)NC1C(C)OC(=O)[C@H](CC(=O)C2=CC=CC=C2N)NC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)CNC1=O)[C@H](C)CC(O)=O

Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii

4-dimethylphenyl)-N-[(1E)-[(2

ATX inhibitor 5 20529 Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(NC2=CC=C(C=C2)N2CCN(CCOCCOCCNC(=O)CNC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CC2)=NC=C1ClATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor, with an IC50 of 15. 3 nM. ATX inhibitor 5 shows anti hepatofibrosis effects and reduces CCl4 induced hepatic fibrosis level prominently. Product information CAS Number: 2402772 45 4 Molecular Weight: 474. 87 Formula: C22H18ClF3N6O Chemical Name: N' [(1E) (4 chlorophenyl)methylidene] 4 {[3 (trifluoromethyl)phenyl]amino} 5H,6H,7H,8H pyrido[4,3 d]pyrimidine 6 carbohydrazide Smiles:

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