Imatinib Impurity E PEG3-amine-Boc CAS Number: 2114339-57-8

CAS Number: 2114339-57-8

0 mM) inhibited JMJD2A and HG-induced proliferation in a concentration-dependent way

but is highly selective with regard to other enzymes

8 days) produces a concentration-related inhibition of serum-stimulated cell growth with an IC50 value of 1

Imatinib Impurity E PEG3-amine-Boc CAS Number: 2114339-57-8Imatinib Impurity E is the impurity of Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR ABL, v Abl, PDGFR and c kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS CoV and MERS CoV. Product