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addition of AS19 (1 μM) completely restores T-cell proliferation after 48 hours
CAS Number: 1566586-52-4
CAS Number: 775294-82-1
CAS Number: 475498-26-1
BIBU 1361 dihydrochloride Catalog No.:M21988-C addition of AS19 (1 μM)BIBU 1361 dihydrochloride is a selective inhibitor of epidermal growth factor receptor (EGFR) kinase with an IC50 value of 0. 038 0. 007 M [1, 2]. The EGFR signaling pathway is associated with multiple intracellular signaling events that promote proliferation and survival. It plays a key role in the progression of glioblastoma multiforme (GBM) . In glioma cells, EGFR signaling can induce the phosphorylation of Akt, Erk1 2 and STAT3. BIBU 1361
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