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10(3):e0116409
12-dienoate
mice) shows improved efficacy (regression) in a 92
CN1C2=CC(=CC=C2N=C1COC1C=CC(CC2SC(=O)NC2=O)=CC=1)OC1C=C(C)C(N)=C(C)C=1
Nigericin e alcohol 10(3):e0116409Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K+ H+ ionophore, promoting K+ H+ exchange across mitochondrial membranes. Nigericin can be a NLRP3 activator that induces the release of IL 1 as a NALP3 dependent manner. Nigericin triggers eryptosis, an effect paralleled by ROS formation, and in part due to induction of oxidative stress. Nigericin triggers apoptosis. Product information CAS Number: 28380 24 7 Molecular
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