Oxindole (Indolin-2-one) vinostat) Smiles: OC1=C(NC2=CC=CC=C21)C1=NC2=CC=CC=C2C1=O

Smiles: OC1=C(NC2=CC=CC=C21)C1=NC2=CC=CC=C2C1=O

Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat

and metastatic melanoma cells (SK-MEL-5

tuberculosis growth in vitro under iron-limited conditions

Oxindole (Indolin-2-one) vinostat) Smiles: OC1=C(NC2=CC=CC=C21)C1=NC2=CC=CC=C2C1=OOxindole (Indolin 2 one) is an aromatic heterocyclic building block. 2 indolinone derivatives have become lead compounds in the research of kinase inhibitors. Oxindole (Indolin 2 one) is a bicyclic structure consisting of a benzene ring fused to 2 pyrrolidone. Substituted indolinones can be referred as 'privileged structures' owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold.