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(S,R,S)-AHPC-C2-PEG4-N3 potassium Temsirolimus treatment for 2 weeks

SKU: 62063836252

4.6
USD100.00 USD124.00

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Description

Temsirolimus treatment for 2 weeks also delays the growth of rapamycin-resistant U251 xenografts by 148%

CC1=CC=C(CN2CCNCC2)C=C1NC(=O)CNC1=CC(F)=C(F)C=C1

[Fasudil hydrochloride]

24)25)29-19(31)12-4-6-32(7-5-12)20-14-9-28-30-18(14)26-11-27-20

(S,R,S)-AHPC-C2-PEG4-N3 potassium Temsirolimus treatment for 2 weeks(S, R, S) AHPC C2 PEG4 N3 (VH032 C2 PEG4 N3) is a synthesized E3 ligase ligand linker conjugate that incorporates the (S, R, S) AHPC based VHL ligand and 4 unit PEG linker used in PROTAC technology. (S, R, S) AHPC C2 PEG4 N3 can be used in the synthesis of vRucaparib TP4 (HY 130647). vRucaparib TP4 a highly potent PARP1 degrader with a half maximal degrading concentration (DC50) of 82 nM. Product information Molecular Weight: 703. 85 Formula:

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