Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation InChi: InChI=1S/C25H25FN2O3S/c1-16-6-9-18(10-7-16)32(30

InChi: InChI=1S/C25H25FN2O3S/c1-16-6-9-18(10-7-16)32(30

with an IC50 value of 400±40 nM

EGFR or insulin receptor tyrosine kinases or MEK

1-(2-ethoxyethyl)-2-(4-methyl-1

Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation InChi: InChI=1S/C25H25FN2O3S/c1-16-6-9-18(10-7-16)32(30Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP competitive second generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0. 9 nM and an IC50 of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dimesylate causes double stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti tumor activity. Product information CAS Number: 1234015