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11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b
and cell cycle arrest of MLL-AF6-transformed cells
Chembridge-5861528 is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx (IC50 values are 14
SU5416 (25 mg/kg
Chlorpyrifos 10 TFA 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[bChlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression. Product