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BMS-794833 - CAS# 1174046-72-0 itor 1 (R enantiomer hydrochloride) Gressens P

SKU: 65248021825

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Description

Gressens P

TGFβ1 downregulated the mRNA level of CDH1 and upregulated the mRNA levels of FN1

Verlukast was in clinical development for the treatment of asthma and related diseases

but only kill cells with MLL rearrangement

BMS-794833 - CAS# 1174046-72-0 itor 1 (R enantiomer hydrochloride) Gressens PBMS 794833 is a potent ATP competitive inhibitor of Met VEGFR2 with IC50 of 1. 7 nM 15 nM. BMS 794833 also inhibits Ron (Met family), Axl (phylogenetically related Axl Tyro3 Mer subfamily) and Flt 3 with IC50 values less than 3 nM. The compound was selective versus a panel of greater than 200 additional receptor tyrosine kinase (RTKs), non RTKs and serine threonine kinases based on biochemical or Ambit binding assays. Moreover, it inhibited the cell

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